(1954- ) is an American molecular geneticist. He is perhaps one of the most influential scientist in genomics if not the most.
He is currently Professor of Genetics at Harvard Medical School and Professor of Health Sciences & Technology [2 at Harvard and MIT. With Walter Gilbert he developed the first direct genomic sequencing method in 1984and helped initiate the Human Genome Project in 1984 [4 while he was a Research Scientist at newly-formed Biogen Inc. He invented the broadly-applied concepts of molecular multiplexing and tagshomologous recombination methods [6, and DNA array synthesizers. Technology transfer of automated sequencing & software to Genome Therapeutics Corp. resulted in the first commercial genome sequence, (the human pathogen, Helicobacter pylori) in 1994 He initiated the Personal Genome Project (PGP) [8 in 2005 and research on synthetic biology. He is director of the U.S. Department of Energy Center on Bioenergy at Harvard & MIT and director of the National Institutes of Health (NHGRI) Center of Excellence in Genomic Science at Harvard, MIT & Washington University [10. He has been advisor to 22 companies, most recently co-founding (with Joseph Jacobson, Jay Keasling, and Drew Endy) Codon Devices, a biotech startup dedicated to synthetic biologyand (with Chris Somerville) founding LS9, which is focused on biofuels [12. He is a senior editor for Nature EMBO Molecular Systems Biology.
See also
Personal Genome ProjectExternal links
- George Church in Wikipedia.org
- Church Lab webpage
- New Polony DNA Sequencing Methods
- Biosketch on Edge.org
References
- ^ HMS Genetics Faculty
- ^ HST
- ^ Church GM, Gilbert W (1984). "Genomic Sequencing". Proc Nat Acad Sci USA 81: 1991-5. PMID 6326095.
- ^ Cook-Deegan RM (1989). "The Alta summit, December 1984". Genomics 5: 661-3. PMID 2613249.
- ^ Church GM, Kieffer-Higgins S. (1984). "Multiplex Sequencing". Science 240: 185-8. PMID 3353714.
- ^ Link AJ, Phillips D, Church GM (1997). "Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization". J Bacteriol. 179: 6228-37. PMID 9335267.
- ^ (1996) "Capitalizing on the genome". Nature Genetics 13: 1. PMID 8673083.1
- ^ Church GM (2005). "The personal genome project". Mol Syst Biol. 1: 0030. PMID 16729065.
- ^ DOE Genomes to Life Center
- ^ Centers of Excellence in Genomic Science Awards
- ^ Herper M (2006). "Photoshop For DNA". Forbes.2
- ^ San Francisco Business Times - March 12, 2007
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